Publications

 

  1. Cochrane, R.W., Robino, R.A., Granger, B., Allen, E., Vaena, S., Romeo, M.J., de Cubas, A.A., Berto, S., Ferreira, L.M.R., 2024. High affinity chimeric antigen receptor signaling induces an inflammatory program in human regulatory T cells. Mol Ther Methods Clin Dev 32(4): 101385

  2. Barra, J.M., Robino, R.A., Castro-Gutierrez, R., Proia, J., Russ, H.A., Ferreira, L.M.R., 2024. Combinatorial genetic engineering strategy for immune protection of stem cell-derived beta cells by chimeric antigen receptor regulatory T cells. Cell Rep 43 (11):114994

  3. Sytsma, B.J., Allain, V., Bourke, S., Faizee, F., Fathi, M., Berdeaux, R., Ferreira, L.M.R., Brewer, J., Li, L., Pan, F.L., Rothrock, A.G., Nyberg, W.A., Li, Z., Wilson, L.H., Eyquem, J., Pawell, R.S., 2024. Scalable intracellular delivery via microfluidic vortex shedding enhances the function of chimeric antigen receptor T-cells. bioRxiv doi:10.1101/2024.06.25.600671

  4. Wang, F., Ferreira, L.M.R., Mazzanti, A., Yu, H., Gu, B., Meissner, T.B., Li, Q., Strominger, J.L., 2024. Progesterone-mediated remodeling of the maternal-fetal interface by a PGRMC1-dependent mechanism. J Reprod Immunol 163:104244

  5. Cochrane, R.W., Robino, R.A., Granger, B., Allen, E., Vaena, S., Romeo, M.J., de Cubas, A.A., Berto, S., Ferreira, L.M.R., 2024. High affinity chimeric antigen receptor signaling induces an inflammatory program in human regulatory T cells. bioRxiv doi:10.1101/2024.03.31.587467

  6. Cochrane, R.W., Fiorentino, A., Allen, E., Robino, R.A., Quiroga, J., Ferreira, L.M.R., 2024. How to test human CAR T cells in solid tumors, the next frontier of CAR T cell therapy. Methods Mol Biol 2748:243-265

  7. Zimmerman, C.M., Robino, R.A., Cochrane R.W., Dominguez, M.D., Ferreira, L.M.R., 2024. Redirecting human conventional and regulatory T cells using chimeric antigen receptors. Methods Mol Biol 2748:201-241

  8. Tennant, M.D., New, C., Ferreira, L.M.R., O’Neil, R.T., 2023. Efficient T cell adoptive transfer in lymphoreplete hosts mediated by transient Stat5 signaling. Mol Ther 31 (9), 2591-2599

  9. Ferreira, L.M.R., 2023. Conference report: Advanced Therapies Week 2023. Regen Med 18(4):297-299

  10. Skartsis, N., Muller, Y.D., Ferreira, L.M.R., 2023. Regulatory T cell homeostasis: requisite signals and implications for clinical development of biologics. Clin Immunol 246: 109201

  11. Ghobadinezhad, F., Ebrahimi, N., Mozaffari, F., Moradi, N., Beiranvand, S., Pournazari, M., Rezaei-Tazangi, F., Khorram, R., Afshinpour, M., Robino, R., Aref, A.R., Ferreira, L.M.R., 2022. The emerging role of regulatory cell-based therapy in autoimmune disease. Front Immunol 13:1075813

  12. Skartsis, N., Ferreira, L.M.R., Tang, Q., 2022. The dichotomous outcomes of TNFa signaling in CD4+ T cells. Front Immunol 13:1042622

  13. Khosravi-Maharlooei, M., Madley, R., Borsotti, C., Ferreira, L.M.R., Sharp, R.C., Brehm, M.A., Greiner, D.L., Parent, A.V., Anderson, M.S., Sykes, M., Creusot, R.J., 2022. Modeling human T1D-associated autoimmune processes. Mol Metab 56:101417

  14. Skartsis, N., Peng, Y., Ferreira, L.M.R., Nguyen, V., Ronin, E., Muller, Y.D., Vincenti, F., Tang, Q., 2021. IL-6 and TNFa drive extensive proliferation of human Tregs without compromising their lineage stability or function. Front Immunol 12:783282

  15. Ferreira, L.M.R., Muller, Y.D., 2021. CAR T-cell therapy: is CD28-CAR heterodimerization its Achilles’ heel? Front Immunol 12:766220   

  16. Muller, Y.D., Ferreira, L.M.R., Ronin, E., Ho, P., Nguyen, V., Faleo, G., Zhou, Y., Lee, K., Leung, K.K., Skartsis, N., Kaul, A.M., Mulder, A., Claas, F.H.J., Wells, J.A., Bluestone, J.A., Tang, Q., 2021. Precision engineering of an anti-HLA-A2 chimeric antigen receptor in regulatory T cells for transplant immune tolerance. Front Immunol 12:686439

  17. Muller, Y.D., Nguyen, D.P., Ferreira, L.M.R., Ho, P., Raffin, C., Valencia, R.B., Congrave-Wilson, Z., Roth, T., Eyquem, J., Van Gool, F., Marson, A., Perez, L., Wells, J.A., Bluestone, J.A., Tang, Q., 2021. The CD28-transmembrane domain mediates chimeric antigen receptor heterodimerization with CD28. Front Immunol 12:639818

  18. Gershteyn, I.M., Burov, A.A., Miao, B.Y., Morais, V.H., Ferreira, L.M.R., 2020. Immunodietica: interrogating the role of diet in autoimmune disease. Int Immunol 32 (12), 771-783

  19. Ferreira, L.M.R., Mostajo-Radji, M.A., 2020. Plasma-based COVID-19 treatments in low- and middle-income nations pose a high risk of an HIV epidemic. npj Vaccines 5, 58

  20. Watson, A., Ferreira, L.M.R., Hwang, P., Xu, J., Stroud, R., 2020. Peptide antidotes to SARS-CoV-2 (COVID-19). bioRxiv doi:10.1101/2020.08.06.238915

  21. Ferreira, L.M.R., Li, A.M., Serafim, T.L., Sobral, M.C., Alpoim, M.C., Urbano, A.M., 2020. Intermediary metabolism: An intricate network at the crossroads of cell fate and function. Biochim Biophys Acta Mol Basis Dis 1866 (10), 165887

  22. Yu, H., Rimbert, A., Palmer, A.E., Toyohara, T., Xia, Y., Xia, F., Ferreira, L.M.R., Chen, Z., Chen, T. Loaiza, N., Horwitz, N.B., Kacergis, M.C., Zhao, L., BIOS Consortium, Soukas, A.A., Kuivenhoven, J.A., Kathiresan, S., Cowan, C.A., 2019. GPR146 deficiency protects against hypercholesterolemia and atherosclerosis. Cell 179 (6), 1276-1288.e14

  23. Abreu, P.L., Ferreira, L.M.R., Cunha-Oliveira, T., Alpoim, M.C., Urbano, A.M., 2019. HSP90: A Key Player in Metal-Induced Carcinogenesis? Heat Shock Protein 90 in Human Diseases and Disorders. Heat Shock Proteins. Asea A., Kaur P. (eds), ISBN: 978-3-030-23158-3, Springer

  24. Ferreira, L.M.R., Cunha-Oliveira, T., Sobral, M.C., Abreu, P.L., Alpoim, M.C., Urbano, A.M., 2019. Impact of carcinogenic chromium on the cellular response to proteotoxic stress. Int J Mol Sci 20 (19), E4901

  25. Ferreira, L.M.R., Muller, Y.D., Bluestone, J.A., Tang, Q., 2019. Next-generation regulatory T cell therapy. Nat Rev Drug Discov 18, 749-769

  26. Carosso, G.A., Ferreira, L.M.R., Mostajo-Radji, M.A., 2019. Developing brains, developing nations: Can scientists be effective non-state diplomats? Front Educ 4, 95

  27. Carosso, G.A., Ferreira, L.M.R., Mostajo-Radji, M.A., 2019. Scientists as non-state actors of public diplomacy. Nat Hum Behav 3, 1129–1130

  28. Ferreira, L.M.R., Carosso, G.A., Duran, N.M., Bohorquez-Massud, S.V., Vaca-Diez, G., Rivera-Betancourt, L.A., Rodriguez, Y., Ordonez, D.G., Alatriste-Gonzalez, D.K., Vacaflores, A., Auza, L.G., Schuetz, C., Alvarado-Arnez, L.E., Alexander-Savino, C.V., Gandarilla, O., Mostajo-Radji, M.A., 2019. Effective participatory science education in a diverse Latin American population. Palgrave Comm 5, 11

  29. Gershteyn, I.M., Ferreira, L.M.R., 2019. Immunodietica: A data-driven approach to investigate interactions between diet and autoimmune disorders. Journal of Translational Autoimmunity 1, 100003

  30. Han, X., Wang, M., Duan, S., Franco, P.J., Kenty, J.H.R., Hedrick, P., Xia, Y., Allen, A., Ferreira, L.M.R., Strominger, J.L., Melton, D.A., Meissner, T.B., Cowan, C.A., 2019. Generation of hypoimmunogenic human pluripotent stem cells. Proc Natl Acad Sci USA 116 (21), 10441-10446

  31. Abreu, P.L., Cunha-Oliveira, T., Ferreira, L.M.R., Urbano, A.M., 2018. Hexavalent chromium, a lung carcinogen, confers resistance to thermal stress and interferes with heat shock protein expression in human bronchial epithelial cells. Biometals 31 (4), 477-487

  32. Tilburgs, T., Meissner, T.B., Ferreira, L.M.R., Mulder, A., Musunuru, K., Ye, J., Strominger, J.L., 2017. NLRP2 is a suppressor of NF-kB signaling and HLA-C expression in human trophoblasts. Biol Reprod 96 (4), 831-842

  33. Ferreira, L.M.R., Meissner, T.B., Tilburgs, T., Strominger, J.L, 2017. HLA-G: at the interface of maternal-fetal tolerance. Trends Immunol 38 (4), 272-286

  34. Ferreira, L.M.R., Tang, Q., 2017. Generating antigen-specific regulatory T cells in the fast lane. Am J Transplant 17 (4), 851-853

  35. Ferreira, L.M.R., Meissner, T.B., Mikkelsen, T.S., Mallard, W., O’Donnell, C.W., Tilburgs, T., Gomes, H.A.B., Camahort, R., Sherwood, R.I., Gifford, D.K., Rinn, J.L., Cowan, C.A., Strominger, J.L., 2016. A distant trophoblast-specific enhancer controls HLA-G expression at the maternal-fetal interface. Proc Natl Acad Sci USA 113 (19), 5364-5369

  36. Meissner, T.B., Mandal, P.K., Ferreira, L.M.R., Rossi, D.J., Cowan, C.A., 2014. Genome editing for human gene therapy. Methods Enzymol 546, 273-295

  37. Mandal, P.K., Ferreira, L.M.R., Collins R., Meissner T.B., Boutwell C.L., Friesen M., Vrbanac V., Garrison B.S., Stortchevoi A., Bryder D., Musunuru K., Brand H., Tager A.M., Allen T.M., Talkowski M.E., Rossi D.J., Cowan C.A., 2014. Efficient Ablation of Genes in Human Hematopoietic Stem and Effector Cells using CRISPR/Cas9. Cell Stem Cell 15(5), 643-652

  38. Abreu, P.L., Ferreira, L.M.R., Alpoim, M.C., Urbano, A.M., 2014. Impact of hexavalent chromium on mammalian cell bioenergetics: phenotypic changes, molecular basis and potential relevance to chromate-induced lung cancer. Biometals 27(3), 409-443

  39. Ferreira, L.M.R., 2013. Gammadelta T cells: innately adaptive immune cells? Int Rev Immunol 2(3), 223-248

  40. Ferreira, L.M.R. and Mostajo-Radji, M.A., 2013. How induced pluripotent stem cells are redefining personalized medicine. Gene 520 (1), 1-6

  41. Mostajo-Radji, M.A. and Ferreira, L.M.R., 2012. Changing cell identity to create true personalized medicine. Gac Med Bol 35(2), 76-79

  42. Ferreira, L.M.R., Floriddia, E.M., Quadrato, G., Di Giovanni, S., 2012. Neural regeneration: lessons from regenerating and non-regenerating systems. Mol Neurobio. 46, 227-241

  43. Ferreira, L.M.R., Hebrant, A., Dumont, J.E., 2012. Metabolic reprogramming of the tumor. Oncogene 31(36), 3999-4011

  44. Urbano, A.M., Ferreira, L.M.R., Alpoim, M. C., 2012. Molecular and cellular mechanisms of hexavalent chromium-induced lung cancer: an updated perspective. Curr Drug Metab 13(3), 284-305

  45. Urbano, A.M., Ferreira, L.M.R., Cerveira, J.F., Rodrigues, C.F., Alpoim, M.C., 2011. DNA Damage, Repair and Misrepair in Cancer and in Cancer Therapy. DNA Repair and Human Health, Sonya Vengrova (ed.), ISBN: 978-953-307-612-6, InTech

  46. Ferreira, L.M.R., 2010. Cancer metabolism: The Warburg effect today. Exp Mol Pathol 89, 372-380